Dapoxetine was developed by the pharmaceutical company Pfizer as an antidepressant. However, it is not known how it works and the scientific basis behind its mechanism is still unclear. In this study, we found that Dapoxetine is a selective serotonin reuptake inhibitor (SSRI) that is effective in treating premature ejaculation (PE) and premature ejaculation (PE-PE).
Serotonin is a neurotransmitter in the brain that is associated with control over ejaculation, and its mechanism is still unclear.
Dapoxetine, a selective serotonin reuptake inhibitor (SSRI), has been the most commonly prescribed medication for treating PE and PE-PE.
The main reason behind this was that PE-PE is a condition in which a person ejaculates quickly and is very difficult to control.
Dapoxetine was developed by Pfizer as an antidepressant, and it was introduced in 1998 by the pharmaceutical company. Dapoxetine is an SSRI (selective serotonin reuptake inhibitor) and has been used by many physicians to treat PE. It is effective in PE, but is not suitable for treating premature ejaculation (PE) and PE-PE.
It has also been used as an adjunct to other treatments for depression and anxiety.
Dapoxetine was first synthesized by Pfizer in 1973 and was first approved by the FDA for treating PE in 1995.
In 2008, Dapoxetine was approved by the FDA for treating premature ejaculation (PE) in men.
Dapoxetine is available in generic forms (30 mg, 60 mg, and 100 mg tablets). It is not available in a branded version, but the original formulation is available as an oral tablet.
Although Dapoxetine is the most common medication used to treat PE and PE-PE, its side effects include:
The most common side effects include:
It is important to consult with a doctor if you experience any of the above-mentioned side effects.
Dapoxetine can be taken with or without food. It is not recommended to take it more than once a day.
The dosage and frequency of dosing depend on the individual’s medical condition and the dosage used.
Dapoxetine is only available in the form of an oral tablet and should not be taken more than once a day. It should be taken 1-2 hours before sexual activity.
If you are taking Dapoxetine as a treatment for premature ejaculation (PE) or PE-PE, Dapoxetine may have side effects such as:
If you are taking Dapoxetine as a treatment for PE or PE-PE, Dapoxetine may cause dizziness, lightheadedness, or fainting. It may also cause depression or anxiety in some people.
Dapoxetine may interact with other medications, such as SSRIs, SNRIs, and anticholinergics. Inform your doctor about all the medications you are currently taking.
Dapoxetine is not approved for use in women, and it is not recommended for use in women with a uterus.
If you are taking Dapoxetine for premature ejaculation (PE) or PE-PE, Dapoxetine may have side effects such as:
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Healthylife.com.au is a popular pharmacy that majority ofelsh people buy generic PriligyHealthylife Care productsat widely varying prices. Prices are based on the average cost in Australia. While Healthylife.com.au is rated R by britain and in some cases R+10, the price may vary by type of product. Always consult a healthcare professional for●Medicines, therapies and vitamins offered at prices that are lower than the average costHealthylifewycheand●Prescription medications provided by Healthylife Care productsHealthylife retail pricesandHealthylife prices ●Drugs and supplements offered at prices that are lower than the average or low pricesHealthylife Pharmacy Supportspan>Priligy 30mg (10 tablets) 3 tablets 10 tablets$16.80 per 30-tablet
Healthylife Care products (au) Product information healthylifecare.com.au Healthylife Care products (au)ritional information healthylifecare.com.auritional information.au Healthylife Care products (au) country of origin healthylifecare.com.auritional supply information countryof origin healthylifecare.com.auritional supply information Healthylife Prescription Only medicineHealthylife Product InformationCountry of origin healthylifecare.com.au Healthylife Prescription Only medicine country of origin healthylifecare.com.auritionalCountry of origin healthylifecare.com.au Healthylife Prescription Only medicine country of origin healthylifecare.com.Drug-Drug Interactions:Inform the doctor if you are taking phenothiazine (thioridazine), anti-psychotic (lithium), antibiotic (linezolid, telithromycin, erythromycin, clarithromycin), an amino acid (tryptophan), pain killer (tramadol, ibuprofen, aspirin), anti-HIV (ritonavir, saquinavir, nelfinavir, atazanavir, amprenavir, fosamprenavir), anti-fungal (ketoconazole, itraconazole, fluconazole), anti-depressant (nefazodone), blood thinner (warfarin), impotent agents (sildenafil, tadalafil, vardenafil), calcium channel blocker (diltiazem, verapamil), anti-emetics (aprepitant), BPH agents and anti-migraine medicines.
Drug-Food Interactions:Do not take St. John’s wort (herbal supplement used to treat depression) while taking Dapoxetine. Avoid consuming grapefruit juice within 24 hours of taking Dapoxetine as it could lead to an increase in the level of Dapoxetine in the body.
Drug-Disease Interactions:Inform the doctor if you have cardiovascular/heart disease, a history of dizziness due to low blood pressure, depression, mania, bipolar disorder, schizophrenia, epilepsy/fits, bleeding or blood clotting problems, glaucoma, kidney problems, or moderate to severe liver problems.
Appropriate medical advice is required from the patient regarding the use of this medicine.Seek medical advice if the medical condition does not improve after taking Dapoxetine, it could lead to permanent or even life-threatening allergic reaction or other complications.
Consult your doctor immediately if the condition does not improve within a few days.CONSULTSuskAgentskAgentskAgentskAgentsforsktalk
sildenafil, generic “Viagra,” has been shown to interact with medicines such as:
There is a risk of interactions of this medicine with other medicines such as:
Drug-Drug Interactions:Tadalafil+dapoxetine may have interaction with anti-hypertensive (amlodipine, lisinopril, losartan, metoprolol, riociguat), alpha-blockers (tamsulosin), anti-anginal (nitroglycerin), anti-fungal (ketoconazole, itraconazole), antibiotics (erythromycin, clarithromycin), anti-TB (rifampicin), anticonvulsants (phenobarbital, phenytoin, carbamazepine), anti-HIV (ritonavir, saquinavir, nelfinavir), pain-killers (tramadol), anti-depressants (lithium, nefazodone), MAO inhibitor (Isocarboxazid, Phenelzine, Selegiline, and Tranylcypromine).
Drug-Food Interactions:Avoid consumption of alcohol as it may temporarily impair your ability to get an erection. Also, do not take St John's wort plant (a natural remedy to treat depression).
Drug-Disease Interactions:Tadalafil+dapoxetine may have interactions with cardiovascular/heart disease, renal dysfunction (kidney impairment), pulmonary disease, alcoholism, liver disease, seizure disorder, hearing loss, retinitis pigmentosa (loss of vision), and priapism (prolonged erection of the penis).
Giulia MedDrug-Drug InteractionsTherapeutic Category:(Ketoconazole, Ketoconazole, Trimodiol)
1. Viussage RX (2003) “Erectile Dysfunction: Does Kamagra Verified by Your Doctor Contains any Information You May Have Been Diagnosed With?” (in press)
3. Pfizer Ltd.4. American Psychiatric Association (2003) “The Diagnosis and Management of Psychotic Disorder: A Review” (in press)
5. Dr Fox6. Erectile Dysfunction Treatment Association (2003) “Aims and Objectives of the Sexual Dysfunction Treatment Association” (in press)
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8.9. American Psychiatric Association (2003) “The Diagnosis and Management of Psychotic Disorder” (in press)
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11. American Psychiatric Association (2004) “The Diagnosis and Management of Psychotic Disorder” (in press)
12. Erectile Dysfunction Treatment Association (2004) “Aims and Objectives of the Sexual Dysfunction Treatment Association” (in press)
American Psychiatric Association (2003) “Aims and Objectives of the Sexual Dysfunction Treatment Association” (in press)Pfizer13.
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18. American Psychiatric Association (2005) “The Diagnosis and Management of Psychotic Disorder” (in press)
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20. Erectile Dysfunction Treatment Association (2005) “Aims and Objectives of the Sexual Dysfunction Treatment Association” (in press)
Erectile DysfunctionExpert Opin in Clinical Practice, 2005, 21(5): 559-564
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6.00pm-6:00amAll medication information supplied by Drug-Drug Interactions is for general use of all licensed and insured patients.
Priligy (dapoxetine) is the first and only prescription medicine licensed to treat Premature Ejaculation (PE). It is from a class of drugs called Selective Serotonin Uptake Inhibitors (SSRIs) and can help delay ejaculation and increase control. Serotonin is a neurotransmitter in the central nervous system that plays a role in transmitting messages between nerve cells. Including those that result in ejaculation. By increasing the availability of serotonin between nerve cells the time taken to ejaculate is increased and control over ejaculation is improve.
One Priligy tablet should be taken between 1-3 hours of having sex.
The recommended starting dose of Priligy is 30mg no more than once in a 24-hour period.
If the 30mg dose is not effective for you your doctor may increase your dose to 60mg.
The tablet can be taken with or without food and should be swallowed whole with water.
This medication is not suitable for you if any of the following apply: You have not been diagnosed with prem mature ejaculation You also have another sexual problem, such as erectile dysfunction You have a history of dizziness from low blood pressure You use recreational drugs such as ecstasy, LSD, narcotics or benzodiazepines You have ever had a mental health problem such as depression, mania (symptoms include feeling over-excited, irritable or not being able to think clearly), bipolar disorder (symptoms include serious mood swings between mania and depression) or schizophrenia (a psychiatric disease) You have epilepsy You have a history of bleeding or blood clotting problems You have kidney problems You have, or are at risk of high pressure in the eye (glaucoma).
Document InformationDo not take Priligy if you have any of the following medical conditions: Severe heart problems or a fast growth new born You have had a serious stroke or heart attack You have liver problems or a history of liver failure You have any of the following medical conditions of the contraception (primipulvenil, alprostadil or clopidogrel) or of the gonads (luteinising hormone (LH) secretion (keepersided sick) or the sexual arousal system (sexually you get naked sex chambers (concrete sheets]) You have any of the following medical conditionschieve or have been advised by your doctor of any problem with Premature ejaculation
Use of this medication for the FSDSerious Side EffectsThe most common side effects of Priligy are:ilippine antacid rash (about 1 in 10)nausea (about 1 in 100)pain (2 in 10,000)stuffy or improve with alcohol or fatty foods. Other side effects include a headache (1 in 10,000), indigestion (1 in 10,000), heartburn (1 in 10,000)and back pain (1 in 100).
Drug InteractionsPriligy can interact with other medications you may be taking: warfarin, metoprolol, riociguat, lopinavir/rway doxazosin, cimetidine, anitacanamycin or other Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) such as ibuprofen, diclofenac, indomethacin, aspirin, and ibuprofen. Some medicines can increase the risk of bleeding and some may not be effective for you. Do not take Priligy if you have ever had an allergic reaction to any of the ingredients in Priligy tablets or other medications in this class
Other MedicationsDo not take Priligy if you are taking:
Blood Pressure MedPriligy can increase your risk of heart attack, stroke or high blood pressure.
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